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U.S.-listed cannabis stocks are back in focus as expectations build around a potential shift in federal marijuana policy.  Markets have reacted positively to reports that President Donald Trump is considering directing regulators to reclassify cannabis from Schedule I to Schedule III under the Controlled Substances Act. While such a move would not legalize marijuana outright, it would mark the most significant federal reform in decades, easing regulatory pressure, reducing punitive taxes, and potentially attracting institutional capital.  The prospect has already sparked a sharp rally in cannabis equities, suggesting investors are positioning ahead of possible policy action before the end of 2025. At the center of this optimism is the potential rollback of Section 280E, which prevents cannabis companies from deducting ordinary and necessary business expenses.  Reclassification would materially improve after-tax profitability and cash flow, while better access to banking and capital markets could support valuation expansion, particularly for scaled and financially disciplined operators. Against this backdrop, a select group of U.S.-listed cannabis stocks appears well-positioned if regulatory momentum continues. Tilray Brands (NASDAQ: TLRY) Tilray Brands (NASDAQ: TLRY) stands out as a direct beneficiary of renewed optimism around federal reform after spending the past two years strengthening its financial profile. In its latest quarter, the company reported about $200 million in revenue, with cannabis contributing just under half and beverages and wellness products making up a growing share. Adjusted EBITDA turned positive at roughly $13 million, and Tilray returned to quarterly net profitability after posting losses a year earlier. The company ended the quarter with more than $400 million in cash and marketable securities and reduced near-term debt, reinforcing its balance sheet while many peers remain capital-constrained. These gains matter because Tilray’s valuation is highly sensitive to regulatory shifts and investor sentiment. As a liquid Nasdaq-listed stock, it is often a…

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Filed under: News - @ December 14, 2025 8:22 pm